Name: N,O-Bis(trimethylsilyl)trifluoroacetamide;

Alias: N,O-Bis(trimethylsilyl)trifluoroacetamide; N,O-bis(trime.silyl)trifluoroacetamide; N,O-bis(trimethylsilyl)acetamide,*with 10%; BSTFA; N,O-Bis-(trimethylsilyl)-trifluoroacetamide; N,O-Bis(trimethylsily)trifluoroamide; Acetamide, 2,2,2-trifluoro-O,N-bis(trimethylsilyl)-; Ethanimidic acid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester; N,O-bis(trimehylsilyl)trifluoroacetamide; N,O-BSTFA; Trimethylsilyl (1Z)-2,2,2-trifluoro-N-[(Z)-trimethylsilyl]ethanimidoate; 2,2,2-TRIFLUORO-N,O-BIS(TRIMETHYLSILYL)-ACETAMIDE; LABOTEST-BB LT00453960; BIS(TRIMETHYL)TRIFLUOROACETAMIDE; N,N-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE; SILYLATING MIXTURE FLUKA V; REGISIL RC-1; REGISIL RC-2; REGISIL RC-3; REGISIL(R) RC-1; REGISIL(R) RC-2; REGISIL(R) RC-3; Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate; N.O-Bis(trimethylsilyl)trifluoro acetamide (BSTFA); bis(Trifluoromethylsilyl)trifluoroacetamideBSTFA

Molecular formula: C₈H₁₈F₃NOSi₂

Molecular weight: 257.40

CAS Registry Number: 25561-30-2

EINECS number: 247-103-9

InChI: 1S/C8H18F3NOSi2/c1-14(2,3)12(15(4,5)6)7(13)8(9,10)11/h1-6H3

Physical and chemical properties

Appearance: colorless transparent liquid

Melting point: -10ºC

Boiling point: 142ºC

Water solubility: hydrolyses

Refractive index: 1.3829-1.3849

Flash point: 23ºC

Density: 1.018 g/cm³

Safety Information

Safety Instructions:

S16: Keep away from ignition sources.

S26: If splashed in eyes, flush with plenty of water and get medical attention immediately.

S45: if cause an accident or feel discomfort when handing chemicals, seek medical help immediately (preferably with the product container label).

S36/37/39: Wear appropriate protective clothing, gloves and use protective glasses or face shield.

Hazardous material symbol:

Corrosive substance

Hazardous Category Code:

R10: Flammable.

R34: Can burn the skin and eyes.

Additional Information

Product Application: Pharmaceutical intermediate or medicine intermediate. Derivatization reagent for the detection of melamine by GC-MS or GC-MS/MS.

N,O-bis(trimethylsilyl)trifluoroacetamide is an important pharmaceutical intermediate, mainly used as a neutral silylation reagent in the silylation protection of amino, ammonia Chemical book acid, phenol, carboxylic acid and enol, as a mild neutral silylation reagent, it not only has high reaction activity and good selectivity, but also has the advantages of high reaction yield and simple post-treatment.

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